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. 2019 Apr;17(1):28–38. doi: 10.2174/2211352516666180927111546

Table 2.

Physico-chemical data of synthesized Chalcone derivatives (3AP-3JP).

Compound Code Mol. Formula Mol.wt Melting Point (°C) Color Rf Solubility Yield (% w/w)
3AP C20H20ClN3O 353.84 137-140 °C Pale orange, amorphous 0.24* Soluble in petroleum ether, Chloroform, DMSO, DMF 45.58%
3BP C20H20ClN3O 353.84 115-120 °C Light brown, amorphous 0.51* 55.65%
3CP C20H20ClN3O 353.84 120-125 °C Light brown, crystals 0.41* 42.85%
3DP C20H20N4O3 364.32 142-145 °C Lemon yellow, amorphous 0.30* 69.44%
3EP C20H20N4O3 364.32 130-135 °C Pale yellow, amorphous 0.31* 66.66%
3FP C20H20N4O3 364.32 126-132 °C Red, amorphous 0.33* 22.39%
3GP C21H23N3O2 349.00 130-134 °C Yellow, amorphous 0.26** 56.65%
3HP C22H23N3O 345.00 112-116 °C Lemon yellowish, crystals 0.35* 48.53%
3IP C20H21N3O 319.00 83-88 °C Light brown, crystals 0.39** 48.42%
3JP C20H20FN3O 337.00 123-126 °C Lemon yellow, crystals 0.21** 63.36%

Solvent front used for TLC are * = n-Hexane: Ethyl acetate (6:4) * * = n-Hexane: Ethyl acetate (8:2).