Table 2.
Compound Code | Mol. Formula | Mol.wt | Melting Point (°C) | Color | Rf | Solubility | Yield (% w/w) |
---|---|---|---|---|---|---|---|
3AP | C20H20ClN3O | 353.84 | 137-140 °C | Pale orange, amorphous | 0.24* | Soluble in petroleum ether, Chloroform, DMSO, DMF | 45.58% |
3BP | C20H20ClN3O | 353.84 | 115-120 °C | Light brown, amorphous | 0.51* | 55.65% | |
3CP | C20H20ClN3O | 353.84 | 120-125 °C | Light brown, crystals | 0.41* | 42.85% | |
3DP | C20H20N4O3 | 364.32 | 142-145 °C | Lemon yellow, amorphous | 0.30* | 69.44% | |
3EP | C20H20N4O3 | 364.32 | 130-135 °C | Pale yellow, amorphous | 0.31* | 66.66% | |
3FP | C20H20N4O3 | 364.32 | 126-132 °C | Red, amorphous | 0.33* | 22.39% | |
3GP | C21H23N3O2 | 349.00 | 130-134 °C | Yellow, amorphous | 0.26** | 56.65% | |
3HP | C22H23N3O | 345.00 | 112-116 °C | Lemon yellowish, crystals | 0.35* | 48.53% | |
3IP | C20H21N3O | 319.00 | 83-88 °C | Light brown, crystals | 0.39** | 48.42% | |
3JP | C20H20FN3O | 337.00 | 123-126 °C | Lemon yellow, crystals | 0.21** | 63.36% |
Solvent front used for TLC are * = n-Hexane: Ethyl acetate (6:4) * * = n-Hexane: Ethyl acetate (8:2).