Table 3.

Multivariate analysis for predictors of myopenia in CRC patients

Variable	Univariate			Multivariate
	OR	95% CI	P value	OR	95% CI	P value
Gender (female)	2.33	1.27–4.3	0.007 *	2.5	1.13–5.53	0.024 *
Age (>68 years old)a	1.57	0.86–2.85	0.14
Histological type (undifferentiated)	0.46	0.16–1.29	0.14
Location (left)	0.62	0.33–1.17	0.14
T classification (pT3/4)	2.06	1.04–4.05	0.036 *	1.07	0.41–2.79	0.89
Vessel involvement (present)	1.93	1.05–3.53	0.034 *	0.75	0.3–1.88	0.54
Lymphatic vessel involvement (present)	2.58	1.21–5.5	0.014 *	1.97	0.62–6.26	0.25
Lymph node metastasis (present)	2.72	1.47–5.04	0.001 *	1.71	0.72–4.07	0.22
Distant metastasis (present)	3.06	1.49–6.31	0.002 *	1.42	0.5–4.07	0.51
Pre‐operative haemoglobin (low)b	4.11	2.18–7.77	<0.0001 *	3.1	1.36–7.08	0.007 *
Pre‐operative lymphocytes (low)b	0.55	0.27–1.09	0.09
Pre‐operative albumin (low)b	4.69	2.44–9.02	<0.0001 *	3.21	1.36–7.58	0.008 *
Pre‐operative serum miR‐203 (high)b	5.46	2.32–12.8	0.0001 *	5.16	1.8–14.8	0.002 *

CI, confidence interval; CRC, colorectal cancer; OR, odds ratio.

^aThe median age at surgery is 68 years in CRC patients.

^bCut‐off thresholds of each covariate were determined by receiver operating characteristic analysis with Youden's index for myopenia in each gender of CRC patients.

^* P < 0.05. Bold font means significant p‐value in these tables.