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. 2019 Jun 24;7:e7165. doi: 10.7717/peerj.7165

Figure 5. Effect of SpostC on HIF-1α, BNIP3 and Beclin-1 protein expression after H/R injury.

Figure 5

(A) Western blot images of each group; (B) HIF-1α protein expression; (C) BNIP3 protein expression; (D) Beclin-1 protein expression; SpostC significantly upregulated HIF-1α and BNIP3 protein expression while decreasing Beclin-1 protein expression. After 2ME2 administration, the expression of HIF-1α and BNIP3 was downregulated. Data represent mean ± SD (n = 3/group) (*P < 0.05 vs C group, #P < 0.05 vs H/R group, &P < 0.05 vs SpostC group).