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. 2017 Apr 19;37(16):4391–4404. doi: 10.1523/JNEUROSCI.1619-16.2017

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Copyright © 2017 the authors 0270-6474/17/374391-14$15.00/0

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Figure 8. — Intrathecal injection of Kv4.3/KChIP1/DPP10 cDNAs attenuates SNL-evoked pain. Rats received the SNL surgery following the baseline (BL) measurement on D0. Mechanical and thermal hypersensitivity developed in the hindpaw at the ipsilateral (ipsi) but not contralateral (contra) side (A, B). After intrathecal injection (inj.) of Kv4.3 cDNA (A, B) or Kv4.3/KChIP1/DPP10 cDNAs (C, D) at the ipsilateral side on D4, mechanical hypersensitivity was attenuated (A, C), but thermal hypersensitivity remained (B, D). Data are mean ± SEM (n = 6). *p < 0.05, compared with BL. ^#p < 0.05, compared with D4 (Tukey's post hoc test after one-way ANOVA). ^##p < 0.01, compared with D4 (Tukey's post hoc test after one-way ANOVA). ^###p < 0.001, compared with D4 (Tukey's post hoc test after one-way ANOVA).