Table 1.
Identity of peptides showing a genotype-specific increase in oxidized cysteine following CORT treatment
| Accession No. | Protein name | Peptide sequence | Site of oxidation | WT/CORT(−) vs KO/CORT(−) | WT/CORT(+) vs KO/CORT(+) |
|---|---|---|---|---|---|
| P17563 | Selenium binding protein 1 | FLHDPSATQGFVGCALSSNIQR | 278Cys | 0.91 | 1.56 |
| P35438 | Glutamate receptor, ionotropic, NMDA1 (zeta 1) | CDLVTTGELFFR | 744Cys | 0.80 | 1.52 |
| P39053 | Dynamin 1 | CVDMVISELISTVR | 427Cys | 0.87 | 1.54 |
| P40142 | Transketolase | TVPFCSTFAAFFTR | 386Cys | 0.78 | 1.90 |
| P46460 | N-ethylmaleimide sensitive fusion protein | THPSVVPGCIAFSLPQR | 59Cys | 0.78 | 1.60 |
| P60487 | Pyridoxal (pyridoxine, vitamin B6) phosphatase | CGMTTVLTLTGVSSLEEAQAYLTAGQR | 246Cys | 0.81 | 4.21 |
| P97300 | Neuroplastin | LTLEDSGTYECR | 116Cys | 0.94 | 1.49 |
| Q01097 | Glutamate receptor, ionotropic, NMDA2B (epsilon 2) | ICDLMSDR | 86Cys | 0.80 | 1.43 |
| Q02053 | Ubiquitin-like modifier activating enzyme 1 | VGEFCHSR | 178Cys | 1.00 | 1.57 |
| Q61699 | Heat shock 105 kDa/110 kDa protein 1 | SVLDAAQIVGLNCLR | 167Cys | 0.75 | 1.51 |
| Q8R5H6 | WASP family 1 | HLCHTALPR | 14Cys | 1.05 | 1.51 |
| Q99PJ0 | Neurotrimin | EQSGEYECSASNDVAAPVVR | 201Cys | 1.13 | 1.42 |
| Q9CZ13 | Ubiquinol-cytochrome c reductase core protein 1 | NALVSHLDGTTPVCEDIGR | 410Cys | 1.00 | 1.37 |
| LCTSATESEVTR | 380Cys | 0.95 | 1.50 | ||
| Q9R111 | Guanine deaminase | FTLSCTETLMSELGNIAK | 218Cys | 1.16 | 1.67 |
| GASIAHCPNSNLSLSSGLLNVLEVLK | 301Cys | 0.92 | 1.84 | ||
| Q9R1V6 | Disintegrin and metallopeptidase domain 22 | SGAAYIGGICSLLR | 347Cys | 0.90 | 1.36 |
| Q9Z0S1 | Bisphosphate 3′-nucleotidase 1 | SHSNQLVTDCISAMNPDTVLR | 206Cys | 0.98 | 1.40 |
Peptides with an ion score of >20 were retrieved. These peptides are listed on the basis of a difference of >1.30 in the ratio between WT/CORT(+) and KO/CORT(+) and within 0.75–1.25 in the ratio between WT/CORT(−) and KO/CORT(−). Underlining indicates Cys.