Figure 2.

Voxelwise whole-brain fMRI results for Study 1 (N = 108; top row) and Study 2 (N = 70; bottom row) projected on a coronal slice (y = −1) of an anatomical template image. Across studies, shock anticipation (threat cue vs safe cue) is consistently associated with BOLD fMRI responses in the basal forebrain region encompassing the bilateral BNST (left column) whereas shock confrontation (shock vs baseline) produced robust bilateral amygdala BOLD responses (right column). Images shown at whole-brain p < 0.05 FEW-corrected except for Study 2, anticipation phase, where the threshold is p < 0.005 uncorrected to show the significant activation of the BNST (FWE small volume-corrected p < 0.05).