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In vitro analysis of rs6039769 in N2a cells. Quantification of the SNAP25 expression level was estimated using a luciferase reporter gene under control of the human SNAP25 promoter region containing either the C or the A allele of rs6039769. Both constructs showed a higher reporter expression level than the empty vector. The C allele showed a 20% increase of the reporter expression level than the A allele. The values are reported as the mean ± SD. ***p < 0.0001.
