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. 2017 Oct 25;37(43):10389–10397. doi: 10.1523/JNEUROSCI.1040-17.2017

Figure 4.

Figure 4.

Structural and functional prefrontal limbic network characterization in regard to SNAP25 genotype. A, Amygdala volume in patients with schizophrenia and unaffected control subjects. Males homozygous for the SNAP25 rs6039769 C at-risk allele have a larger amygdala than non-risk carriers (AA or AC) or than females regardless of their genotype. B, Amygdala–VMPFC connectivity in patients with schizophrenia and unaffected control subjects. Again, males homozygous for the SNAP25 rs6039769 C at-risk allele have a higher connectivity than non-risk carriers (AA or AC) or than females regardless of their genotype. Squares show males, and circles show females. Black symbols show individuals with CC genotype and clear symbols show those with AA or AC genotype. Individual results are reported with mean values ± SD.