Electrode placements and 6-OHDA lesion. A, Localization of recording electrodes in sagittal rat brain sections at 4 lateral-to-medial levels indicated in millimeters relative to midline (for details, see Materials and Methods: Recording device and surgery). B, Representative coronal section immunostained for TH at the level of substantia nigra. There is an absence of immunopositive neurons in substantia nigra in the 6-OHDA-injected side of the brain (right). SN, Substantia nigra; Str, striatum.