Table 2.
Basic properties of the hyperpolarization-activated current (Ih) in WT and Fmr1 KO LSO neuronsa
| Current (nA) at −95 mV | Maximum half-activation (mV) | |
|---|---|---|
| P21 | ||
| WT (n = 10) | 2.64 ± 0.13 | −71.02 ± 1.09 |
| Fmr1 KO (n = 12) | 2.47 ± 0.22 | −70.54 ± 1.47 |
| p | 0.53 | 0.79 |
aVoltage-clamp recordings were obtained in the presence of the following (in mm): 1 3,4-diaminopyridine, 10 TEA-Cl, 0.2 BaCl2, 0.001 TTX, 0.05 NiCl2, 0.1 CdCl2, 0.01 DNQX, 0.025 dl-AP5, and 0.001 strychnine, to block other voltage-gated conductances.