Table 3.
Active membrane properties in response to the first suprathreshold current pulse in WT and Fmr1 KO LSO neuronsa
| AP width (ms) | Latency (ms) | AP amplitude (pA) | Voltage threshold (mV) | |
|---|---|---|---|---|
| P8 | ||||
| WT (n = 17) | 0.57 ± 0.04 | 10.09 ± 0.91 | 76.06 ± 1.6 | −28.27 ± 1.1 |
| Fmr1 KO (n = 16) | 0.60 ± 0.04 | 17.24 ± 1.36 | 80.26 ± 1.9 | −30.91 ± 1.0 |
| p | >0.99 | <0.001 | 0.67 | 0.59 |
| P14 | ||||
| WT (n = 16) | 0.376 ± 0.034 | 4.73 ± 0.56 | 67.04 ± 1.57 | −26.49 ± 1.0 |
| Fmr1 KO (n = 15) | 0.26 ± 0.01 | 2.25 ± 0.18 | 66.50 ± 1.47 | −29.43 ± 0.9 |
| p | >0.99 | 0.04 | >0.99 | 0.69 |
| P21 | ||||
| WT (n = 39) | 0.21 ± 0.005 | 3.11 ± 0.18 | 65.49 ± 1.1 | −26.24 ± 0.6 |
| Fmr1 KO (n = 20) | 0.24 ± 0.01 | 2.28 ± 0.1 | 66.74 ± 0.91 | −24.59 ± 1.3 |
| p | >0.99 | 0.72 | >0.99 | >0.99 |
ap values: two-way ANOVA followed by Bonferroni post-tests.