Table 1.
Mean and SEM levels of freezing behavior prior to CS presentations in each experiment
| Experiment | Group | Training | Test | Extinction | Test ABB | Test ABA |
|---|---|---|---|---|---|---|
| Experiment 1 | Lever | 0.4 (0.4) | 1.0 (0.4) | |||
| None | 0.0 (0.0) | 1.7 (1.0) | ||||
| Experiment 2 | Lever-eYFP | 2.9 (1.4) | 4.6 (1.7) | |||
| Lever-Hm4Di | 2.6 (1.2) | 5.7 (2.5) | ||||
| Lever+-eYFP | 0.2 (0.2) | 0.0 (0.0) | ||||
| Lever+-hM4Di | 0.8 (0.4) | 1.7 (1.0) | ||||
| Experiment 3 | ||||||
| Stage I | eYFP | 0.8 (0.4) | 2.1 (1.3) | |||
| hM4Di | 3.1 (1.8) | 6.3 (2.9) | ||||
| Stage II | eYFP | 1.0 (0.0) | 1.5 (1.5) | |||
| hM4Di | 2.0 (0.0) | 1.0 (0.5) | ||||
| Experiment 4 | Sated-eYFP | 4.4 (2.9) | 63.3 (10.2) | |||
| Sated-hM4Di | 1.3 (0.8) | 53.5 (13.0) | ||||
| Hungry-eYFP | 0.4 (0.4) | 60.6 (14.1) | ||||
| Hungry-hM4Di | 0.0 (0.0) | 50.0 (12.4) | ||||
| Experiment 5 | eYFP | 10.4 (8.8) | 1.3 (0.9) | 11.3 (5.1) | 2.9 (0.8) | |
| hM4Di | 4.4 (3.1) | 2.1 (1.9) | 6.3 (2.7) | 3.3 (3.1) |