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Anesthesia time was independent of the number of antecedent propofol boluses given. A, In rats given 2 (n = 60), 3 (n = 50), 4 (n = 20), or 5 (n = 7) consecutive bolus doses of propofol mean anesthesia time was the same on the first bolus as on the nth. B, Lines represent anesthesia times of 60 individual rats upon repeated bolus dosing (all at HUJI). To ease separation, lines representing the seven rats given five consecutive doses are colored. Error bars in A indicate ±SD.
