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. 2017 Nov 22;37(47):11335–11352. doi: 10.1523/JNEUROSCI.1223-17.2017

Figure 5.

Figure 5.

Encocannabinoid-dependent suppression of PC synaptic transmission is unchanged by TFR1 deletion. A, Superimposed parallel fiber–EPSCs by two successive parallel fiber stimulations in the absence (basal) and presence of DHPG in control and cKO mice. The bar graph shows the percentage changes of first EPSC amplitudes relative to basal values. The scatterd points show changes in PPD. B, Examples of climbing fiber–EPSCs in response to paired stimuli in control and cKO mice. Records obtained before (basal) and during the presence of DHPG are superimposed. The bar graph shows percentage changes of first EPSC amplitudes relative to basal values. Control: 58 ± 8% (n = 10). cKO: 60 ± 5% (n = 10). p = 0.34. The right panel shows changes in PPD. Control: 0.57 ± 0.04 (basal) and 0.76 ± 0.07 (DHPG), n = 10. cKO: 0.59 ± 0.05 (basal) and 0.80 ± 0.08 (DHPG), n = 10. p = 0.52. n.s., Not significant.