Figure 5.

cGSN promotes remyelination in a rat LPC demyelination model. A, Remyelinated axons in the LPC-induced demyelination lesions were visualized by electron microscopy. Arrowhead denotes the remyelinated axon in a GSN-treated animal. Scale bar, 2 μm. B, Quantification of remyelinated axons per field by toluidine blue staining from each treatment group. n = 30 fields/3 animals/group. p = 0.0007, t = 3.589, two-tailed unpaired Student's t test. C, Schematic diagram showing the experimental timeline.