Table 2.

Characteristics of spontaneous recurrent seizures and C-SWDs

Spontaneous recurrent seizures Incidence: 64% of mice presented at least 1 spontaneous seizure during the first 6 weeks after virus injection Onset of spontaneous seizures: 9.5 ± 1.86 d after AAV injection 50% of mice with seizures presented first seizure before day 6 Frequency of seizures: 5.3 ± 0.83 seizures/month Mean seizure duration: 24.6 ± 0.62 s Preictal C-SWD: 89.5% of spontaneous seizures were preceded by C-SWDs

C-SWDs Incidence: 88% of mice 50% of mice with seizures presented first C-SWD before day 5 Number of SWDs per C-SWD: 42.1 ± 3.14 Frequency of SWDs within C-SWDs: 0.14 ± 0.005 Hz Number of C-SWDs: 40.0 ± 9.07 per month/mouse Mean duration of C-SWDs: 294 ± 13.7 s

Data are presented as the mean ± SEM.