Figure 5.

Calpain inhibition in the NAc core without retrieval or 6 h after retrieval or after unpaired context exposure had no effect on the expression of cocaine cue memories. A, B, Microinjection of calpain inhibitors without memory retrieval did not disrupt cocaine reward memories (n = 10–11 per group). C, D, Inhibition of calpain activity in the NAc core 6 h after memory retrieval had no effect on cocaine-induced CPP (n = 10 per group). E, F, Calpain inhibitor infusion in the NAc core had no effect on the retrieval of cocaine cue memories itself (n = 11 per group). G, H, Microinjection of calpain inhibitors in the NAc core after exposure to the unpaired context had no effect on cocaine cue memories (n = 7–9 per group). The data are expressed as mean ± SEM.