Fig. 1.

Schema of GSMN rescue process. $\mathcal{M}$, original GSMN with growth reaction X+Y → Z+Biomass. $\mathcal{M}\mathcal{\text{'}}$, expanded GSMN with the full set of rescue (r_x) and help (h_x) reactions for every metabolite x in the biomass reaction. $\mathcal{M}\mathcal{\text{'}}\mathcal{\text{'}}$, example of a minimal rescued GSMN in the particular case where only metabolite Y needs to be rescued