Skip to main content
. 2019 Mar 29;10(3):696–709. doi: 10.1002/jcsm.12412

Figure 3.

Figure 3

Free amino acid content is reduced in 4E‐BP1/2 DKO skeletal muscle. (A) Statistical heat map displaying the fold‐change values observed when amino acid abundances were compared between the WT and 4E‐BP1/2 DKO quadriceps of 24‐month‐old mice. The dark green colour is used to indicate statistically significant decreases P < 0.05, while the light green indicates differences that trended towards significance with a 0.05 < P < 0.1. (B) Real‐time PCR quantification of amino acid transporter mRNA expression in quadriceps from WT and 4E‐BP1/2 DKO 24‐month‐old mice. (C) Real‐time PCR quantification of mRNA expression of genes involved in branched‐chain amino acid catabolism in quadriceps from WT and 4E‐BP1/2 DKO 24‐month‐old mice. n = 6 in each genotype.