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. 2019 Jun 27;14(6):e0218410. doi: 10.1371/journal.pone.0218410

Table 4. Time trends in mortality rates by cause of death, before, during and after the 2008 economic crisis, in the Spanish women aged 15 to 64 years.

Annual Percentage Change (APC), 95% confidence interval (95% CI) and p value.

Causes of death (ICD-10 code1) 2005–2007 (Before crisis) 2008–2010 (During crisis) 2011–2013 (During crisis) 2014–2016 (After crisis)
APC (95% CI) p value APC p value APC p value APC p value
All causes -1.0 (-1.9, -0.1) 0.038 -2.1 (-2.7, -1.5) < 0.001 -1.1 (-1.7, -0.6) < 0.001 -0.6 (-1.2, 0.0) 0.065
Cancer (C00-C97) -0.1 (-1.4, 1.2) 0.897 -0.2 (-0.9, 0.6) 0.626 -0.4 (-1.1, 0.3) 0.280 -0.8 (-1.6, -0.1) 0.038
Cardiovascular diseases (I00-I99) -3.6 (-5.9, -1.2) 0.004 -5.1 (-6.5, -3.7) < 0.001 -1.6 (-3.1, -0.1) 0.035 -0.6 (-2.2, 1.0) 0.461
Digestive disease (K00-K93) -1.3 (-5.4, 2.9) 0.535 -3.0 (-5.5, -0.5) 0.023 -4.8 (-7.2, -2.3) < 0.001 -1.3 (-4.1, 1.5) 0.370
Respiratory disease (J00-J99) 2.9 (-1.8, 7.8) 0.236 -3.0 (-5.6, -0.2) 0.037 -3.4 (-6.0, -0.7) 0.015 5.8 (2.8, 8.8) < 0.001
Infectious disease (A00-B99) -3.0 (-8.0, 2.2) 0.257 -10.4 (-13.4, -7.3) < 0.001 -3.0 (-6.4, 0.5) 0.094 -4.9 (-8.7, -1.0) 0.016
Motor vehicle accidents2 -11.2 (-15.8, -6.2) < 0.001 -17.3 (-20.5,-14.0) < 0.001 -8.8 (-12.9, -4,5) < 0.001 3.7 (-1.6, 9.3) 0.183
Suicide (X60-X84+Y87.0) 1.2 (-4.4, 7.0) 0.690 -6.0 (-9.2, 2.8) < 0.001 12.0 (8.5, 15.6) < 0.001 -2.3 (-5.4, 1.0) < 0.001

1. ICD-10: International Classification of Diseases, 10th revision

2. Motor vehicle accidents: V02-V04+V09.0+V09.2+V12-V14+V19.0-V19.2+V19.4-V19.6+V20-V79+V80.3-V80.5+V81.0-V81.1+V82.0-V82.1+ V83-V86+V87.0-V87.8+V88.8-V88.9+V89.0-V89.2