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. 2019 Jun 17;15(6):e1007893. doi: 10.1371/journal.ppat.1007893

Fig 3. Stearoyl-CoA desaturase activity is required for the induction of an innate immune response in C. elegans.

Fig 3

A. Dot plots showing the NanoString nCounter gene expression analysis of 118 immune and stress response genes in C. elegans grown on the indicated RNAi bacteria and exposed to control or R24. Each dot represents one gene. Red dots highlight the 16 genes whose R24-mediated induction is significantly suppressed in fat-6(RNAi) animals. Data are the average of two independent replicates. B. The expression of the 16 fat-6-dependent genes in the indicated genotypes and conditions is shown relative to wild-type animals exposed to control. Significance was determined using t-tests, * p<0.05. Data are the average of two independent replicates, each normalized to three control genes and expressed relative to the baseline condition (wild-type animals exposed to control) for each gene. Error bars show standard deviation.