. 2019 Jun 18;25:4527–4534. doi: 10.12659/MSM.914426

Table 2.

Correlation between preoperative plasma fibrinogen, serum albumin, mean platelet volume (MPV), and the neutrophil-to-lymphocyte ratio (NLR) with clinicopathological features of the patients with laryngeal squamous cell carcinoma (LSCC) treated with surgical resection.

	n	Fibrinogen (g/L)			Albumin (g/L)			MPV			NLR
	n	Normal	>4	P-value	Normal	<35	P-value	Normal	<9	P-value	>2.22	≤2.22	P-value
Age (years)
<60	44	31	13	0.094	34	10	0.158	31	12	0.804	31	13	0.094
≥60	66	36	30	0.094	42	24	0.158	49	17	0.804	36	30	0.094
Gender
Male	103	64	39	0.429	72	31	0.674	74	28	0.749	64	39	0.429
Female	7	3	4	0.429	4	3	0.674	6	1	0.749	3	4	0.429
Clinical stage
I–II	53	42	11	<0.01	43	10	0.008	43	9	0.036	39	14	0.009
III–IV	57	25	32	<0.01	33	24	0.008	37	20	0.036	28	29	0.009
T
T1–T2	58	46	12	<0.01	48	10	0.001	47	10	0.025	42	15	0.009
T3–T4	52	21	31	<0.01	28	24	0.001	33	19	0.025	25	27	0.009
N
N0	83	53	30	0.267	58	25	0.754	50	22	0.273	53	30	0.267
N1–N3	27	14	13	0.267	18	9	0.754	22	5	0.273	14	13	0.267
Tumor location
Glottic	72	50	22	0.029	53	19	0.339	57	14	0.082	44	28	0.311
Supraglottic	34	16	18		21	13		21	13		22	12
Subglottic	4	1	3		2	2		2	2		1	3
Histological grade
1	33	16	17	0.615	22	11	0.700	23	10	0.943	22	11	0.441
2	56	41	15		39	17		44	12		33	23
3	21	10	11		15	6		13	7		12	9
Smoking history
No (0)	74	44	30	0.655	52 (0)	22	0.701	56	18	0.320	45	29
Yes (1)	36	23	13	0.655	24	12	0.701	24	12	0.320	25	11
Alcohol
No (0)	91	55	36	0.825	64	12	0.538	68	12	0.303	59	32	0.889
Yes (1)	19	12	7	0.825	12	7	0.538	12	7	0.303	12	7	0.889