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. 2019 Jun 27;14(6):e0218996. doi: 10.1371/journal.pone.0218996

Fig 2. Factors associated with LTL in HIV+ individuals.

Fig 2

LTL was measured using real-time quantitative PCR and expressed as a ratio to a housekeeping gene (T/S ratio). Data shown are normalized to an internal control. Differences in LTL are shown between (a) individuals treated with different cART regimens, (b) individuals with (use) or without (no use) a past history of substance use (cannabis, amphetamines, legal intoxicants, and 5-MeO-DIPT), and (c) individuals who achieved plasma HIV viral loads <40 RNA copies/mL (<40) or failed to achieve this level of control (>40) after 1 year of starting cART. * indicates statistical significance with P value obtained from the Bonferroni–Dunn test; ** indicates statistical significance with P value obtained from the Mann-Whitney U-test. Abbreviations: cART, combination antiretroviral therapy; NNRTI, nonnucleoside reverse transcriptase inhibitor; PI, protease inhibitor, INSTI, integrase strand transfer inhibitor.