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. 2019 Jun 4;129(7):2904–2919. doi: 10.1172/JCI127307

Figure 6. Conditional deletion of epithelial Becn1 affects mesenchymal thinning of the developing lung.

Figure 6

(A) Co-IF staining of CDH1 (green) and vimentin (red) in Becn1Epi-KO and littermate control lungs at E18.5. Nuclei were stained with DAPI (blue). Scale bars: 50 μm; original magnification, ×40 (insets). (B) Representative Western blot for CDH1, vimentin, and fibronectin. Graphs show the densitometric analysis of CDH1 and vimentin expression in whole-lung lysates harvested from Becn1Epi-KO and littermate controls at E18.5. ACTB was used as a protein loading control. Data represent the mean ± SEM (n = 4 separate lungs). *P < 0.05 versus control, by Student’s t test.