Figure 1. GO enrichment analysis links Fra-1 in macrophages to cell proliferation, response to growth factors, and wounding.

Thioglycollate-elicited macrophages were isolated from Fra-1^ΔMx and control mice (n = 2). (A) The deletion efficiency of Fra-1 was quantified by real time PCR (RT-PCR). Data are shown as mean of 2 samples with duplicates and error bars represent SEM. ***P < 0.01, Student’s t test. (B) Heatmap of differentially expressed genes ascertained from microarray analysis. (C–E) GO enrichment analysis of differentially expressed genes found in the microarray analysis (related to Supplemental Figure 2). Depicted are genes associated with the terms in the cluster.