Table 1. The PI3Kγ residues interacting with XL765 are listed with the number of non-bonding interactions and ΔASA.
Interacting residues | Non-bonding interactions | ΔASA (Å2) |
---|---|---|
Lys-802 | 3 | 48.45 |
Met-804 | 1 | 25.32 |
Trp-812 | 5 | 49.81 |
Ile-831 | 1 | 22.3 |
Val-882 | 2 | 14.1 |
Ala-885 | 2 | 26.79 |
Thr-886 | 1 | 22.98 |
Lys-890 | 4 | 59.19 |
Met-953 | 8 | 35.83 |
Ile-963 | 1 | 20.35 |