Table 3. The mTOR residues interacting with XL765 are listed with the number of non-bonding interactions and ΔASA.
Interacting residues | Non-bonding interactions | ΔASA (Å2) |
---|---|---|
Ile-2163 | 2 | 27.24 |
Leu-2185 | 1 | 25.32 |
Trp-2239 | 10 | 56.39 |
Val-2240 | 1 | 8.9 |
Asp-2244 | 3 | 28.52 |
Thr-2245 | 1 | 27.82 |
Ala-2248 | 1 | 16.09 |
Arg-2251 (H-bond) | 6 | 55.76 |
Asp-2252 | 3 | 24.43 |
Met-2345 | 6 | 30.62 |
Ile-2356 | 3 | 31.64 |