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(A–D) Schematic presentation of HSPC and mature hematopoietic cell (NE) localization in the BM relative to the vasculature. Adhesive interactions and cellular distribution are shown under steady state (A) compared with following mobilization with a VLA4 antagonist (B), CXCR2 agonist (C), and the combination of the 2 strategies (D). For a detailed description see the Discussion.
