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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Hepatology. 2019 Mar 15;70(1):84–97. doi: 10.1002/hep.30507

Figure 2. mGPDH deficiency exacerbates HFD-induced hepatic steatosis.

Figure 2.

Liver-specific mGPDH knockout (KO) and cre-control (control) mice were fed with HFD for 12 weeks, and the (A) body weight (BW) (left) and the ratio of liver weight to BW (LW/BW) (right) were determined. (B) Liver lipid contents (TG, TC and NEFA) were determined enzymatically. (C) The serum lipid profiles (TG, TC, LDL, HDL and NEFA) were tested enzymatically. (D) The serum levels of β-hydroxybutyric acid were determined enzymatically. (E) H&E and oil red o staining of liver sections from KO and control mice. Scale bar: 200 or 100 μm. n = 6 mice per group. Data are presented as the mean ± S.E.M. **P < 0.01.