KEY RESOURCES TABLE

REAGENT or RESOURCE	SOURCE	IDENTIFIER
Deposited Data
Raw sequence data	NCBI SRA	Uploaded, pending SRA approval
293T cell expression matrices	10x Genomics	https://support.10xgenomics.com/single-cell-gene-expression/datasets
293T and Jurkat cell mixture expression matrices	10x Genomics	https://support.10xgenomics.com/single-cell-gene-expression/datasets
Human PBMC expression matrices	10x Genomics	https://support.10xgenomics.com/single-cell-gene-expression/datasets
Developing and adolescent mouse CNS expression matrices	(Zeisel et al., 2018)	http://mousebrain.org
Adult mouse brain cell expression matrices	(Saunders et al., 2018)	http://dropviz.org/
M-CSF macrophage expression matrices	(Hie et al., 2019)	http://scanorama.csail.mit.edu
GM-CSF macrophage expression matrices	This paper	http://geosketch.csail.mit.edu
Biological Samples
Human buffy coats	Massachusetts General Hospital	N/A
Software and Algorithms
geosketch Python package	This paper	https://github.com/brianhie/geosketch
Scanorama	(Hie et al., 2019)	https://github.com/brianhie/scanorama
Harmony	(Korsunsky et al., 2018)	https://github.com/immunogenomics/harmonv
SCANPY	(Wolf et al.,2018)	https://scanpv.readthedocs.io/en/latest/