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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Mol Genet Metab. 2018 Dec 27;128(3):288–297. doi: 10.1016/j.ymgme.2018.12.008

Fig 6.

Fig 6.

Partial sequence of the human and murine UROS erythroid-specific promoters showing the GATA1 and CP2 transcription factor binding sites. The location and orientation (<, >) of the GATA1, E-box, and CP2 erythroid binding elements are indicated, as are the four novel promoter mutations causing CEP (−70C, −76A, −86A and −90A). Dots are placed every tenth nucleotide. The homologous CP2 site from the α-globin gene promoter and the GATA1 site from the human stem cell leukemia (SCL) gene promoter are shown.