Table 3. Heat map of IgG reactivities to peanut allergen components, plant profilins, and carbohydrate markers. Ranges of allergen-specific IgG levels are indicated.

Peanut							Profilins						CCD
Asymptomatic Africa	rAra h 1	rAra h 2	rAra h 3	nAra h 6	rAra h 8	rAra h 9	rBet v 2	rHev b 8	rMer a 1	rPhl p 12	rPru du 4	rTri a 12	nCry j 1	nCyn d 1	nCup a 1	MUXF3	nPhl p 4
1	10.05	51.85	≤0.35	35.31	1.67	87.58	8.56	68.41	37.12	4.14	16.27	11.67	12.6	94.31	102.6	43.58	93.05
2	3.89	2.82	≤0.35	≤0.35	≤0.35	89.13	35.86	130.3	75.59	5.92	49.41	41.62	13.6	108	103.8	32.77	80.31
3	1.23	33.03	≤0.35	58.4	2.09	3.82	22.49	67.15	66.6	1.22	45.1	18.12	14.18	19.93	69.01	8.09	22.2
4	0.62	27.22	≤0.35	59.1	4	28.58	16.16	2.29	1.6	1.81	3.55	0.86	29.01	47.13	61.56	12.82	33.69
5	18.38	39.19	≤0.35	37.84	1.4	≤0.35	19.95	114.6	52.01	2.65	43.63	4.11	≤0.35	47.55	100.3	5.41	9.34
6	≤0.35	14.93	≤0.35	17.63	2.36	1.53	13.19	41.2	23	5.29	18.87	10.35	≤0.35	17.53	23.86	7.51	7.1
7	≤0.35	5.69	≤0.35	≤0.35	≤0.35	11.03	18.37	40.74	24.95	≤0.35	18.32	4.65	≤0.35	19.13	46.29	8.71	12.31
8	≤0.35	5.83	≤0.35	3.71	≤0.35	51.23	45.19	4.52	54.24	59.95	≤0.35	3.47	≤0.35	≤0.35	23.35	3.17	2.48
9	≤0.35	8.33	≤0.35	5.16	≤0.35	13.31	5.11	2.96	4.19	3.4	3.33	6.66	3.52	63.65	60.45	38.48	40.22
10	30.7	33.05	≤0.35	24.63	0.82	0.91	3.12	7.88	2.14	0.96	1.33	1.52	2.27	39.9	33.24	12.37	33.95
11	7.11	≤0.35	≤0.35	≤0.35	1.35	1.38	2.32	2.95	1.68	1.03	1.23	1.8	2.23	40.6	32.84	1.87	5.94
12	178.3	130.5	13.13	106.8	2.51	17.92	6	16.46	3.03	1.68	5.08	4.66	≤0.35	26.89	20.55	7.22	≤0.35
13	10.87	8.04	≤0.35	≤0.35	≤0.35	≤0.35	1.14	1.15	0.75	0.42	≤0.35	1.37	1.94	25.49	20.4	9.75	15.58
14	8.86	20.84	3.8	18.44	≤0.35	60.93	0.72	5.38	1.1	≤0.35	1.13	0.48	32.42	39.83	41.42	5.07	13.64
15	2.35	2.28	≤0.35	10.31	≤0.35	1.67	4.52	20.14	15.79	2.04	14.4	8.15	≤0.35	25.05	39.19	3.96	8.22
16	≤0.35	1.06	1.53	≤0.35	3.99	1.01	4.03	7.78	2.97	1.67	3.24	2.6	1.21	34.28	23.15	16.89	43.18
17	13.66	10.3	≤0.35	≤0.35	≤0.35	≤0.35	≤0.35	≤0.35	≤0.35	≤0.35	3.68	≤0.35	≤0.35	14.26	19.61	3.59	5.22
18	9	42.78	19.95	36.47	0.7	22.55	1.08	5.77	1.6	≤0.35	0.89	1.49	51.6	56.83	69.28	1.62	8.68
19	≤0.35	14.94	≤0.35	10.04	1.49	7.03	17.55	47.4	56.25	1.61	29.86	12.22	10.9	20.26	61.7	8.34	23.56
20	103.3	51.46	≤0.35	46.08	3.7	90.72	18.41	81.26	36.71	6.19	21.4	16.96	≤0.35	39.01	24.12	5.21	8.08
21	15.33	28.5	≤0.35	6.92	≤0.35	13.58	≤0.35	≤0.35	≤0.35	≤0.35	≤0.35	≤0.35	25.73	26.75	20.18	7.57	11.72
22	1.55	68.64	57	75.53	3.42	59.16	3.34	10.47	9.79	≤0.35	5.09	1.55	22.09	32.65	39.02	1.99	5.14
23	≤0.35	13.94	14.05	20.23	≤0.35	65.95	4.1	2.04	4.55	1.31	2.5	1.54	22.42	34.23	68.46	16.46	29.49
24	22.68	38.2	19.11	25.64	0.81	11.91	1.72	1.84	2	1.5	0.97	2.9	6.27	115	150.8	8.42	18.43
25	2.62	10.85	≤0.35	14.79	0.64	4.23	1.35	3.71	1.29	≤0.35	1.49	1.08	21.48	8.49	9.65	0.54	2.3
26	6.02	5.77	≤0.35	4.74	≤0.35	6.14	2.78	1.76	0.8	≤0.35	1.18	1.4	10.26	18.62	18.32	0.78	4.71
27	17.24	17.31	31.03	23.18	6.17	20.97	1.21	3.46	2.52	≤0.35	1.14	1.03	15.47	19.33	36.57	4.43	14.57
28	≤0.35	1.19	≤0.35	1.35	≤0.35	1.14	1.44	1.95	≤0.35	≤0.35	≤0.35	0.71	12.03	14.35	14.6	4.56	9.31
29	5.85	14.76	≤0.35	13.3	3.32	120.9	5.49	4.03	2.61	1	≤0.35	1.97	≤0.35	40.69	24.85	≤0.35	6.68
30	3.96	1.08	≤0.35	≤0.35	≤0.35	15.24	0.91	8.65	1.69	≤0.35	1.66	1.32	22.85	11.46	10.38	2.64	9.42
31	3.74	≤0.35	≤0.35	≤0.35	≤0.35	≤0.35	1.6	5.88	1.17	0.71	1.11	2.16	≤0.35	22.77	18.14	1.83	4.05
32	6.48	3.81	≤0.35	≤0.35	≤0.35	35.9	≤0.35	6.65	2.12	1.12	1.78	≤0.35	≤0.35	15.24	1.84	1.32	≤0.35
33	≤0.35	≤0.35	≤0.35	1.25	≤0.35	7.54	≤0.35	2.88	1.8	≤0.35	1.35	≤0.35	12.53	18.75	16.3	3.44	9.55
34	≤0.35	5.36	≤0.35	9.04	1.17	2.69	8.19	2.41	2.07	1.38	1.65	6.58	≤0.35	10.13	72.05	4.78	10.88
35	44.45	44	≤0.35	38.83	2.59	72.4	2.71	18.72	2.4	1.73	3.24	3.75	≤0.35	6.91	6.93	≤0.35	1.82
36	6.32	≤0.35	≤0.35	≤0.35	4.52	14.2	7.02	7.39	≤0.35	1.91	4.58	4.43	≤0.35	19.08	25.25	≤0.35	9.53
37	61.87	57.72	≤0.35	38.66	0.49	0.52	1.15	5.91	1.61	0.59	1.16	0.97	6.38	71.99	77.83	16.78	37.29
38	≤0.35	6.9	≤0.35	≤0.35	2.3	≤0.35	2.41	3.14	3.37	1.79	≤0.35	5.26	≤0.35	20.27	11.37	10.88	6.87
39	6.71	15.21	19.8	18.76	1.88	0.63	8.76	5.08	4.24	1.69	4.29	2.77	16.9	13.57	72.23	9.67	26.53
40	≤0.35	≤0.35	≤0.35	≤0.35	0.59	8.49	0.82	1.96	1.63	≤0.35	0.68	1.13	16.94	19.34	16.95	7.29	10.74
41	≤0.35	≤0.35	≤0.35	≤0.35	1.87	≤0.35	2.88	1.63	3.12	1.46	1.52	3.86	≤0.35	2.34	29.11	1.89	≤0.35
42	30.14	≤0.35	≤0.35	46.09	1.37	4.42	19.33	5.65	9.17	7.19	≤0.35	12.72	≤0.35	12.41	7.43	5.02	7.79
43	≤0.35	≤0.35	≤0.35	≤0.35	≤0.35	≤0.35	2.06	3.39	0.86	0.53	1.06	1.53	≤0.35	2.1	8.09	1.08	3.94
44	1.27	1.13	17.72	1.34	≤0.35	1.06	1.02	1.19	0.53	≤0.35	1.42	0.78	3.07	4.94	7.85	1.24	3.1
45	3.51	6.12	≤0.35	≤0.35	3.69	18.3	8.81	5.53	3.42	3.53	3.25	4.91	≤0.35	8.74	25.9	3.18	4.34
46	≤0.35	38.75	≤0.35	43.64	≤0.35	6.37	4.47	2.79	2.64	3.42	≤0.35	4.32	≤0.35	≤0.35	2.17	2.66	2.05
47	≤0.35	6.8	≤0.35	12.59	0.91	0.87	12.35	1.55	9.78	9.1	1.59	16.79	≤0.35	≤0.35	34.13	≤0.35	≤0.35
48	≤0.35	7.43	1.03	9.53	≤0.35	6.37	5.34	3.4	5.3	≤0.35	1.88	1.03	6.69	2.77	5.95	0.93	1.32
49	6.06	7.15	≤0.35	≤0.35	≤0.35	1.16	1.66	2.48	2.57	0.99	0.69	1.52	22.17	97.55	110.8	40.18	111.3
50	9.44	29.61	≤0.35	36.23	≤0.35	≤0.35	7.24	23.17	2.48	1.88	3.73	3.23	≤0.35	26.57	11.91	≤0.35	≤0.35
51	46.42	70.47	≤0.35	20.55	≤0.35	≤0.35	4.61	39.19	1.17	1.94	2.11	6.66	≤0.35	58.54	34.55	16.72	25.68
52	33.09	13	5.99	20.98	11.81	2.18	≤0.35	6.96	2.25	0.78	1.53	2.38	≤0.35	9.04	10.01	10.02	9.82
53	81.84	52.5	≤0.35	27	1.4	10.26	1.85	6	1.52	0.95	3.25	3.02	1.26	26.47	16.42	7.47	13.59
54	17.2	8.25	≤0.35	2.81	5.95	5.03	8.13	15.51	9.29	3.89	10.96	7.55	3.42	36.35	25.41	12.75	22.74
Median	4.91	9.32	≤0.35	10.18	0.76	6.26	3.69	5.46	2.50	1.27	1.66	2.69	2.09	20.27	25.05	5.05	9.38
Upper quartile	15.80	33.04	≤0.35	29.08	2.32	18.97	8.61	15.75	9.20	1.98	4.36	5.59	13.75	39.85	60.73	9.82	22.34
Lower quartile	≤0.35	2.69	≤0.35	≤0.35	≤0.35	0.99	1.32	2.46	1.58	≤0.35	1.10	1.27	≤0.35	12.17	15.88	1.86	4.27
Peanut							Profilins						CCD
Peanut allergic Sweden	rAra h 1	rArah 2	rAra h 3	nArah 6	rAra h 8	rArah 9	rBet v 2	rHev b 8	rMer a 1	rPhl p 12	rPru du 4	rTri a 12	nCry j 1	nCyn d 1	nCup a 1	MUXF3	nPhl p 4
55	173.5	14.49	4.45	11.2	2.15	1.67	3.7	7.73	4.12	4.38	2.17	3.51	11.71	20.28	18.81	≤0.35	22.21
56	82.52	24.32	4.6	12.47	4.16	5.21	2.79	8.55	2.97	3.9	8.8	1.76	≤0.35	≤0.35	2.38	≤0.35	2.89
57	67.43	15.13	2.45	25.38	2.45	2.04	1.74	1	1.85	1.41	1.3	≤0.35	7.87	0.62	10.06	1.39	3.14
58	117.3	30.13	6.54	48.79	≤0.35	≤0.35	1.1	2.72	1.01	0.75	1.28	1.35	≤0.35	2.01	7.65	≤0.35	0.54
59	25.32	8.83	3.95	6.76	4.07	66.89	2.78	26.24	3.81	2.44	28.26	1.27	9.3	32.46	13.35	≤0.35	33.81
60	154.5	13.06	10.66	15.49	0.79	≤0.35	2.39	1.86	1.95	3.01	1.53	≤0.35	12.66	14.46	20.42	≤0.35	23.81
61	28.42	23.33	16.22	14.06	2.22	3.87	10.25	77.25	31.27	5.29	39.56	10.35	3.18	1.94	9.23	≤0.35	21.03
62	133.9	33.15	18.75	28.53	0.57	3.44	20.84	4.21	12.41	8.63	2.51	7.73	10.07	24.04	13.68	≤0.35	64.52
63	19.8	9.82	4.16	4.28	0.98	≤0.35	1.57	1.06	1.19	1.05	0.81	1.24	3.59	1.88	7.09	0.89	4.85
64	164.5	14.72	≤0.35	12.41	2.48	v	0.92	3	0.95	1.3	3.67	≤0.35	0.91	8.34	3.04	≤0.35	7.81
65	164.9	43.81	22.14	11.35	1.06	≤0.35	4.38	2.21	2.66	4.07	1.77	2.44	11.69	6.2	5.99	≤0.35	8.96
66	74.43	9.08	7.09	23.55	1.48	2.37	0.87	3.87	1.74	1.91	1.46	≤0.35	2.71	≤0.35	2.57	≤0.35	0.77
67	27.28	14.89	4.11	9.02	2.3	1.05	2.11	6.03	4.14	2.29	4.23	2.95	1.74	4.64	3.73	≤0.35	6.7
68	91.17	8.77	6.89	10.54	2.35	1.35	3.9	5.38	3.96	2.96	6.76	≤0.35	13.1	19.89	27.04	≤0.35	30.41
69	34.27	17.35	≤0.35	5.55	2.09	1.18	11.72	2.64	12.46	12.52	1.56	1.61	4.05	17.15	3.8	≤0.35	3.19
70	102.9	5.58	26.17	28.2	≤0.35	≤0.35	≤0.35	2.26	1.31	2.99	0.94	1.13	2.2	12.66	0.77	≤0.35	6.29
71	72.79	17.57	11.13	13.3	1.77	22.21	1.23	10.05	1.54	0.79	2.42	≤0.35	5.91	8.29	29.45	≤0.35	28.29
72	38.48	15.28	0.69	11.69	≤0.35	1.71	13.52	108.3	70.9	4.6	85.55	8.29	≤0.35	5.93	3.1	≤0.35	8.87
73	51.02	14.67	3.63	9.44	1.63	≤0.35	2.23	1.08	1.32	1.02	≤0.35	≤0.35	1.18	3.04	≤0.35	≤0.35	2.39
74	23.52	8	1.5	8.55	1.11	34.89	10.53	24.57	12.54	4.04	15.54	≤0.35	17.78	5.32	56.91	≤0.35	58.15
75	111.7	77.95	12.08	8.95	≤0.35	≤0.35	2.01	2.18	2.32	3.13	1.92	≤0.35	2.06	29.17	4.64	≤0.35	31.86
76	161.7	29.05	5.8	9.15	3.35	≤0.35	1.43	1.52	1.83	1.99	2.16	1.83	6.22	2.21	0.93	≤0.35	1.39
77	9.37	11.75	≤0.35	8.34	4.69	1.05	1.05	2.42	1.43	1	2.92	≤0.35	≤0.35	0.38	3.84	≤0.35	4.04
78	112.3	31.69	13.36	21.74	0.58	≤0.35	3.62	4.16	4.15	2.58	3.28	≤0.35	3.59	1.74	6.97	≤0.35	7.66
79	2.9	27.21	≤0.35	17.7	0.52	2.76	0.62	0.73	1.3	1.49	0.61	≤0.35	4.13	3.27	2.36	≤0.35	18.46
Median	74.43	15.13	4.6	11.69	1.63	1.35	2.23	3	2.32	2.58	2.17	1.13	3.59	5.32	5.99	≤0.35	7.81
Upper quartile	125.6	28.13	11.61	19.72	2.4	3.44	4.14	8.14	4.15	4.06	5.5	2.14	9.69	15.81	13.52	≤0.35	26.05
Lower quartile	27.85	10.79	1.98	8.99	0.58	≤0.35	1.17	2.02	1.38	1.36	1.38	≤0.35	1.46	1.91	2.81	≤0.35	3.17

Allergen-specific IgG levels

ISAC (ISU-G)

≤0.35

0.35-1

1-15

>15