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. Author manuscript; available in PMC: 2019 Jun 27.
Published in final edited form as: Pediatr Allergy Immunol. 2014 Dec 1;25(8):788–795. doi: 10.1111/pai.12310

Figure 5.

Figure 5

Induction of allergen-specific IL10- and TGFβ-dependent control in preventive sublingual immunotherapy (SLIT)-treated patients. Allergen-specific proliferation to the major house-dust mite allergen Der p 1 was assessed in the presence of anti-IL10 or anti -TGFβ antibodies relative to allergen-specific proliferation in the presence of the respective isotype control in the house-dust mite SLIT-treated group (V, n = 10) and the placebo group (P, n = 14). The degree of cytokine-mediated inhibition was calculated as fold increase of proliferation to the respective allergen in the presence of anti-IL10 or anti-TGF-β antibodies as compared to the respective isotype controls and the allergen. V, Verum; P, Placebo; p < 0.05; Wilcoxon-signed rank test.