FIG 6.

Phylogenetic distribution of cdiA alleles. The RBDs (inner ring), TDs (middle ring), and CTs (outer ring) for CdiA1 (A) and CdiA2 (B) were mapped onto maximum likelihood core genome trees of the PABL (red) and NCBI (black) strains. Ring colors represent different variants of the respective domains as noted in Fig. S1 and S3. Branches with dots at the tips indicate a class II C terminus. A red circle means the downstream orphan class V CdiA C terminus is the same as the functional class V CdiA C terminus of the closest phylogenetic neighbor.