Table 2. Comparison of the allele and genotype frequencies of IL-1β-C31T in breast cancer cases and controls.
| IL-1β-C31T | Cases (n = 204) | Controls (n = 210) | OR (95% CI) | p-value | |
|---|---|---|---|---|---|
| Genotype frequencies* | |||||
| CC genotype | 45 (22.1) | 51 (24.3) | 1.0 | - | |
| CT genotype | 89 (43.6) | 117 (55.7) | 0.88 (0.53–1.46) | 0.862‡ | |
| TT genotype | 70 (34.3) | 42 (20.0) | 2.06 (1.16–3.66) | 0.014‡ | |
| Allele frequencies† | |||||
| C allele | 179 (43.9) | 219 (52.1) | - | - | |
| T allele | 229 (56.1) | 201 (47.9) | 1.39 (1.06–1.83) | 0.017 | |
OR = odds ratio; CI = confidence interval.
*Multivariate binary logistic regression analysis; †The χ2 test; ‡Adjusted for body-mass index and family history.