Table 2. Adverse Events of Tacrolimus.
Adverse event* | n (%) |
---|---|
Hypercholesterolemia | 36 (19.5) |
Diarrhea | 30 (16.2) |
BUN/Cr elevation | 28 (15.1) |
Hair loss | 12 (6.5) |
Hyperglycemia | 10 (5.4) |
Hyperphosphatemia | 8 (4.3) |
Hypophosphatemia | 8 (4.3) |
Iron deficiency anemia | 7 (3.8) |
Abdominal discomfort | 7 (3.8) |
Tremor | 5 (2.7) |
Paresthesia | 4 (2.2) |
Eczema | 3 (1.6) |
Headache | 3 (1.6) |
High blood pressure | 3 (1.6) |
Muscle cramp | 3 (1.6) |
Thrombocytopenia | 3 (1.6) |
Tinea pedis, oral fungal infection | 2 (1.1) |
Chills | 2 (1.1) |
Hyperkalemia | 2 (1.1) |
Hypokalemia | 2 (1.1) |
Dizziness | 1 (0.5) |
Myalgia | 1 (0.5) |
Visual disturbances | 1 (0.5) |
Dysmenorrhea | 1 (0.5) |
Oral ulcer | 1 (0.5) |
Nail cracks | 1 (0.5) |
Lower extremity edema | 1 (0.5) |
Total number of adverse events observed | 185 (100.0) |
Number of patients with adverse events | 68/160 (42.5) |
BUN/Cr, blood urea nitrogen/creatinine.
*Adverse events of tacrolimus were either reported by patients or detected in laboratory results. Multiple adverse events occurred concurrently in some patients.