Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jun 27;9:9311. doi: 10.1038/s41598-019-45450-2

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

High field DTI-MRI and histopathology correlation results for rectal cancer tissue specimen 1. The DTI-MRI images shown are (a) A0, (b) ADC map, (c) direction encoded colour fractional anisotropy (FA) map, and (d) FA map. The corresponding histopathology is shown in (e) and (f). The annotated regions on the diffusion tensor image and histopathology (including zoomed images) are: A cancer B desmoplasia C cancer invasion into muscularis propria D fibrous tissue E muscularis propria inner circular layer F muscularis propria outer circular layer and G mucosa. The A0 image was able to identify the band of fibrous tissue which had lower signal intensity. Cancer appeared hypointense on the ADC map, indicating restricted diffusion in cancer. The direction encoded colour FA map was the best MRI image for distinguishing the different tissue regions of interest; cancer and muscularis propria were most clearly distinguished on this image.