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. 2019 Jun 27;9:9311. doi: 10.1038/s41598-019-45450-2

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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High field MRI and histopathology correlation results for rectal cancer tissue specimen 3. The MRI images shown are (a) A0, (b) ADC map, and (c) direction encoded colour fractional anisotropy (FA) map. The annotated regions are diffusion tensor image and histopathology are: A cancer B desmoplasia C muscularis propria inner circular layer D muscularis propria outer longitudinal layer and E heterogeneous regions of granulation tissue and inflammation. The direction encoded colour FA map was the best image to distinguish the different tissue regions of interest; muscularis propria was clearly distinguished from cancer on this image.