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. 2019 Jun 27;9:9311. doi: 10.1038/s41598-019-45450-2

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Box plots of (a) A0, (b) apparent diffusion co-efficient (ADC) and (c) fractional anisotropy (FA) values for each tissue region of interest for all patients. The boxes represent the 25^th to 75^th percentile (interquartile range), the lines within the box represent the median values and the whiskers show the range of values. The dots are outliers. The box plots showed that FA had the clearest contrast between cancer and desmoplasia, fibrous tissue and muscularis propria.