Table 2.
ROC curve Analysis of Biomarkers for LolBHIGH 6 h exposed mice (all brain regions) (Supporting information is in Supplementary Data Tables S1–S4).
| Metabolite | All Brain Regions: ControlVEH vs LolBHIGH | |||||
|---|---|---|---|---|---|---|
| AUCs | Sensitivity (%) | Specificity (%) | 95% Confidence Interval | T-tests | KM Cluster | |
| Leucine | 0.78 | 70% | 70% | 0.65–0.90 | 3.7E-4 | 5.0 |
| Methionine | 0.74 | 80% | 70% | 0.62–0.87 | 4.1E-3 | 1.0 |
| Isoleucine | 0.74 | 60% | 80% | 0.61–0.86 | 9.0E-4 | 5.0 |
| Tyrosine | 0.74 | 80% | 70% | 0.61–0.86 | 1.3E-3 | 1.0 |
| Valine | 0.70 | 60% | 80% | 0.57–0.83 | 1.8E-3 | 2.0 |