Table I.

Study and Patient Characteristics of the Midazolam and Sildenafil PK Studies

	Midazolam	Sildenafil
Indication	Pre-operatively	Pulmonary arterial hypertension
Number of patients	31	156
Number of samples	327	591
Samples/patient*	10 (8–11)	4 (1–4)
Age (years)*	8 (1–17)	10 (1–17)
Body weight (kg)*	30.2 (9.5–83.2)	28.0 (8.2–106.0)
Male/female, n (%)	15/16 (48/52%)	57/99 (37/63%)
Dose (mg)*	12.5 (3–15)	20 (10–80)

*median (range)