Table 3.
Number of AD diagnoses in the BNA from 2016 to 2018
| 2016 (N=115 300) | 2017 (N=115 391) | 2018* (N=86 429) | ||||
| First MMSE ≥20 | First MMSE ≥20 | First MMSE ≥20 | ||||
| No (n=13 952) | Yes (n=13 545) | No (n=17 014) | Yes (n=15 020) | No (n=11 028) | Yes (n=8742) | |
| n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | |
| Depending on the type of centre | ||||||
| Primary memory clinic | 11 043 (79.2) | 10 138 (47.8) | 13 634 (80.1) | 11 268 (75.0) | 8803 (79.8) | 6484 (74.2) |
| CMRR | 2713 (19.5) | 3118 (23.0) | 3193 (18.8) | 3425 (22.8) | 2120 (19.2) | 2029 (23.2) |
| Private neurologist | 196 (1.4) | 289 (2.1) | 187 (1.1) | 327 (2.2) | 105 (1.0) | 229 (2.6) |
| Depending on the diagnostic criteria | ||||||
| AD—former BNA diagnostic criteria | 10 039 (72.0) | 6909 (51.0) | 902 (5.3) | 469 (3.1) | 0 (0.0) | 0 (0.0) |
| AD—clinical syndrome only | 3589 (25.7) | 6053 (44.7) | 15 103 (88.8) | 13 477 (89.7) | 10 452 (94.8) | 8226 (94.1) |
| AD—clinical syndrome and CSF | 288 (2.1) | 550 (4.1) | 903 (5.3) | 1012 (6.7) | 525 (4.8) | 489 (5.6) |
| AD—genetic mutation | 31 (0.2) | 30 (0.2) | 83 (0.5) | 49 (0.3) | 37 (0.3) | 25 (0.3) |
| AD—Down syndrome | 5 (0.0) | 3 (0.0) | 23 (0.1) | 13 (0.1) | 14 (0.1) | 2 (0.0) |
| Depending on the clinical severity | ||||||
| New BNA diagnostic criteria (>2016) | ||||||
| Other (fortuitous discovery) | 38 (0.3) | 63 (0.5) | 159 (0.9) | 127 (0.9) | 103 (0.9) | 91 (1.0) |
| Subjective cognitive complaint | 74 (0.5) | 353 (2.6) | 343 (2.0) | 1077 (7.2) | 248 (2.3) | 781 (8.9) |
| Minor neurocognitive disorder (DSM V) | 464 (3.3) | 2638 (19.5) | 1919 (11.3) | 6205 (41.3) | 1283 (11.6) | 3778 (43.2) |
| Major neurocognitive disorder (DSM V) | 3288 (23.6) | 3536 (26.1) | 13 524 (79.5) | 7039 (46.9) | 9354 (84.8) | 4052 (46.3) |
| Not applicable | 49 (0.4) | 46 (0.3) | 167 (1.0) | 103 (0.7) | 40 (0.4) | 40 (0.5) |
| Former BNA diagnostic criteria (<2016) | ||||||
| Dementia | 9115 (65.3) | 5178 (38.2) | 825 (4.9) | 364 (2.4) | 0 (0.0) | 0 (0.0) |
| Mild cognitive impairment | 750 (5.4) | 1500 (11.1) | 62 (0.4) | 88 (0.6) | 0 (0.0) | 0 (0.0) |
| Other | 172 (1.2) | 223 (1.7) | 15 (0.1) | 16 (0.1) | 0 (0.0) | 0 (0.0) |
| Absence of cognitive complaint | 2 (0.0) | 8 (0.1) | 0 (0.0) | 1 (0.0) | 0 (0.0) | 0 (0.0) |
*Data available up until 18 December 2018.
AD, Alzheimer’s disease; BNA, Banque Nationale Alzheimer; CMRR, Centres de mémoire, de recherche et de ressources (Centres for Research and Resources on Memory); CSF, cerebrospinal fluid; MMSE, mini mental state examination; N, total number of acts registered in the BNA for one given year; n, number of the sample of interest.