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. 2019 Jun 24;9(6):e029663. doi: 10.1136/bmjopen-2019-029663

Table 4.

Comparison between two groups of patients diagnosed with AD or MCI in the BNA in 2014 either in the 11 CMRRs participating in the detailed analysis (Group 1) or in the 18 other French CMRRs

CMRRs P value
Group 0 (n=5 124) Group 1 (n=3 471)
Mean (SD) Mean (SD)
Age 78.12 (10.27) 74.52 (12.07) <0.001
MMSE 20.85 (6.65) 21.71 (6.52) <0.001
n (%) n (%) P value
Gender <0.001
 Female 3314 (64.7) 2080 (59.9)
 Male 1810 (35.3) 1391 (40.1)
Diagnostic <0.001
 AD 3195 (62.4) 1804 (52.0)
 aMCI 595 (11.6) 592 (17.1)
 naMCI 1045 (20.4) 906 (26.1)
 AD and aMCI 118 (2.3) 105 (3.0)
 AD and aMCI and naMCI 19 (0.4) 9 (0.3)
 aMCI and naMCI 152 (3.0) 55 (1.6)
First MMSE <0.001
 <20 1680 (35.9) 825 (28.8)
 ≥20 3000 (64.1) 2039 (71.2)
Education level <0.001
 <12 years 2827 (55.1) 1889 (54.5)
 >12 years 1806 (35.3) 1238 (35.5)
 Missing data 461 (9.6) 350 (10)
Referred to the CMRR by <0.001
 General practitioner 2978 (58.1) 1838 (53.0)
 Neurologist 413 (8.1) 665 (19.2)
 Psychiatrist 102 (2.0) 49 (1.4)
 Geriatrician 243 (4.7) 175 (5.0)
 Other specialist 573 (11.2) 214 (6.2)
 Direct 387 (7.6) 226 (6.5)
 Retirement home 49 (1.0) 26 (0.8)
 Primary memory clinic 17 (0.3) 31 (0.9)
 Other CMRR 24 (0.5) 34 (1.0)
 Hospitalisation unit 310 (6.1) 198 (5.7)
 Emergency unit 12 (0.2) 8 (0.2)
 Social care services 16 (0.3) 7 (0.1)

Group 0 (18 CMRR): Bordeaux, Clermont-Ferrand, Caen, Brest, Rennes, Reims, Corse, Besançon, Paris-Broca, Montpellier, Limoges, Toulouse, Marseille, Angers, Amiens, Grenoble, Villeurbanne, Saint-Etienne.

Group 1 (11 CMRR): Dijon, Lille, Nantes, Vandœuvre-Lès-Nancy, Nice, Paris -Lariboisière, Paris–Pitié Salpêtrière, Poitiers, Rouen, Strasbourg, Tours.

AD, Alzheimer’s disease; aMCI, amnestic mild cognitive impairment; CMRR, Centre for memory research and resource; MCI, mild cognitive impairment; MMSE, Mini Mental State Evaluation; naMCI, non-amnestic mild cognitive impairment.