Table 2.

Associations Between Quintile of Overall and Trimester-specific Antenatal Exposure to UVB and Learning Disability, Scotland, 2000–2010.

		Trimester 1		Trimester 2		Trimester 3		Whole pregnancy
		OR (95% CI)	P value	OR (95% CI)	P value	OR (95% CI)	P value	OR (95% CI)	P value
Univariate	1 (lowest)	Referent		Referent		Referent		Referent
	2	0.98 (0.96–1.01)	0.16	1.00 (0.98–1.03)	0.96	1.05 (1.02–1.07)	<0.01	1.03 (0.98–1.03)	0.80
	3	1.02 (1.00–1.05)	0.07	1.12 (1.10–1.15)	<0.01	1.07 (1.04–1.09)	<0.01	1.09 (1.06–1.12)	<0.01
	4	1.02 (1.00–1.05)	0.06	1.23 (1.20–1.26)	<0.01	1.03 (1.00–1.05)	0.04	1.21 (1.18–1.24)	<0.01
	5 (highest)	0.95 (0.93–0.97)	<0.01	1.20 (1.17–1.23)	<0.01	0.99 (0.96–1.01)	0.26	1.18 (1.15–1.21)	<0.01
Multivariate*	1 (lowest)	Referent		Referent		Referent		Referent
	2	0.98 (0.93–1.04)	0.50	0.96 (0.91–1.02)	0.16	1.14 (1.08–1.20)	<0.01	0.90 (0.86–0.95)	<0.01
	3	0.98 (0.91–1.07)	0.67	0.79 (0.72–0.87)	<0.01	1.33 (1.21–1.47)	<0.01	0.75 (0.70–0.80)	<0.01
	4	0.77 (0.70–0.86)	<0.01	0.65 (0.58–0.72)	<0.01	0.96 (0.86–1.080)	0.52	0.64 (0.59–0.69)	<0.01
	5 (highest)	0.58 (0.52–0.65)	<0.01	0.42 (0.37–0.48)	<0.01	0.48 (0.42–0.55)	<0.01	0.56 (0.51–0.61)	<0.01
Multivariate**	1 (lowest)	Referent		Referent		Referent		Referent
	2	0.98 (0.93–1.04)	0.47	0.96 (0.91–1.02)	0.15	1.14 (1.08–1.20)	<0.01	0.90 (0.86–0.95)	<0.01
	3	0.98 (0.90–1.06)	0.55	0.79 (0.72–0.86)	<0.01	1.34 (1.21–1.48)	<0.01	0.74 (0.69–0.79)	<0.01
	4	0.77 (0.69–0.85)	<0.01	0.64 (0.57–0.72)	<0.01	0.96 (0.86–1.07)	0.47	0.64 (0.59–0.69)	<0.01
	5 (highest)	0.57 (0.51–0.64)	<0.01	0.42 (0.37–0.47)	<0.01	0.48 (0.41–0.54)	<0.01	0.55 (0.51–0.60)	<0.01
Multivariate***	1 (lowest)	Referent		Referent		Referent		Referent
	2	0.95 (0.89–1.01)	0.10	0.91 (0.85–0.98)	0.01	1.04 (0.98–1.11)	0.24	0.84 (0.80–0.88)	<0.01
	3	0.61 (0.54–0.68)	<0.01	0.67 (0.60–0.74)	<0.01	1.14 (1.03–1.27)	0.02	0.61 (0.57–0.66)	<0.01
	4	0.43 (0.38–0.50)	<0.01	0.50 (0.44–0.56)	<0.01	0.86 (0.76–0.97)	0.01	0.55 (0.51–0.60)	<0.01
	5 (highest)	0.34 (0.30–0.40)	<0.01	0.34 (0.30–0.39)	<0.01	0.45 (0.39–0.52)	<0.01	0.50 (0.46–0.55)	<0.01
Multivariate****	1 (lowest)	Referent		Referent		Referent
	2	0.88 (0.82–0.94)	<0.01	0.96 (0.90–1.03)	0.26	1.06 (1.00–1.13)	0.07
	3	0.64 (0.57–0.73)	<0.01	0.70 (0.63–0.78)	<0.01	0.96 (0.84–1.09)	0.51
	4	0.44 (0.37–0.51)	<0.01	0.52 (0.46–0.59)	<0.01	0.63 (0.54–0.73)	<0.01
	5 *highest	0.38 (0.32–0.44)	<0.01	0.36 (0.32–0.42)	<0.01	0.33 (0.28–0.39)	<0.01

CI confidence interval; OR odds ratio.

*Adjusted for month of conception; **also adjusted for child’s sex; ***also adjusted for UVA; ****also adjusted for UVB in other trimesters.