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. 2019 Jun 27;9:9365. doi: 10.1038/s41598-019-45779-8

Table 1.

Animal characteristics and baseline determinations.

Group I Group II Group III Group IV
Age ± SD (Days) 54.2 ± 2.3 55.1 ± 4.2 56.3 ± 2.2 55.8 ± 3.2
Gender (M/F) 3/0 3/0 3/0 3/0
Weight ± SD (Kg) 28.3 ± 1.6 28.9 ± 1.5 28.7 ± 1.3 28.5 ± 1.7
Experimental time (Min) 180 ± 0** 180 ± 0 83 ± 9.8 11.3 ± 2.1
Blood pressure (mmHg)
systolic pressure 93.3 ± 8.5 96 ± 6.2 97.7 ± 9.9 95 ± 9.2
diastolic pressure 52.7 ± 6.1 49 ± 3.6 48.3 ± 7.6 53.3 ± 8.9
Heart rate (n/min) 69.7 ± 5.1 68.3 ± 9.3 62.7 ± 6.5 66.3 ± 6.7
Oxygen saturation (n/%) 97.7 ± 1.5 96.7 ± 3.1 96 ± 1 97.1 ± 2.1
CVP (cm H2O) 7.2 ± 0.7 6.7 ± 0.6 6.8 ± 0.4 7.1 ± 0.3
Cavity temperature (°C) 22.3 ± 0.6 23 ± 1 23.3 ± 0.6 22.7 ± 0.6
ABG
pCO2 (mmHg) 22.4 ± 0.8 23.9 ± 1.1 24.2 ± 1.9 24.8 ± 1.7
pO2 (mmHg) 98.7 ± 1.2 99 ± 1 99.3 ± 0.6 99.7 ± 0.6
pH 7.52 ± 0.07 7.44 ± 0.07 7.46 ± 0.06 7.44 ± 0.14
RLN
Amplitude(uv) 1046 ± 331.9 1253 ± 384.5 1067 ± 210.6 1015 ± 268.8
Latency(ms) 2.09 ± 0.35 1.98 ± 0.34 2.07 ± 0.19 2.12 ± 0.32
VN
Amplitude(uv) 815.3 ± 217.5 859.3 ± 172.3 772.3 ± 70.2 785 ± 134.4
Latency(ms) 10.09 ± 0.19 9.79 ± 0.44 9.71 ± 0.19 9.75 ± 0.43

Group I: intraoperative pressure was kept at 1 times CVP; Group II: intraoperative pressure x2 CVP

Group III: intraoperative pressure x3 times CVP.; Group IV: intraoperative pressure x5 times CVP.

CVP: central venous pressure; ABG: arterial blood gas; RLN: recurrent laryngeal nerve; VN: vagus nerve.

*P < 0.05, **P < 0.01; analysis of the total four groups with Cochran’s and Mantel-Haenszel Chi-square (χCMH2) test, while the variable of side was controlled.

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