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. 2019 May 10;294(25):9901–9910. doi: 10.1074/jbc.RA119.007904

Figure 1.

Figure 1.

Induction of p90RSK phosphorylation correlates with degree of kidney fibrosis. A, C57BL/6 mice were subjected to UUO for 3, 7, and 14 days, followed by Western blotting for phospho- and total p90RSK, fibronectin (Fn), and GAPDH. Numbers indicate individual mouse. B, relative abundance (-fold increase) of phospho- and total p90RSK. *, p < 0.05; ***, p < 0.001 versus control; n = 5 mice/group. C, fibronectin abundance. **, p < 0.01; ***, p < 0.001 versus control; n = 5 mice/group. D, immunofluorescence staining of phospho-p90RSK (green) and FSP-1 (red) in mouse kidneys. Scale bar, 20 μm. CLK, control kidney; T, tubular epithelial cells. Error bars, S.E.