Table 2.

Binding statistics

RPN13 construct	RPN2940–952		RPN2940–952,pTyr950		pTyr preference (-fold change)
	KD	-Fold change	KD	-Fold change
	nm		nm
Wildtype	7.2 ± 0.3		0.9 ± 0.09		8.0
K83A	8.9 ± 0.3	1.2	9.4 ± 0.7	10.4	0.9
K97A	18.0 ± 0.7	2.5	11.2 ± 0.9	12.4	1.6
K97D	67.0 ± 3.5	9.3	427.3 ± 72.8	474.8	0.2
K97E	21.4 ± 1.3	3.0	262.5 ± 31.4	58.2	0.1
R104A	16.8 ± 0.9	2.3	27.2 ± 1.5	30.2	0.6
R104D	42.6 ± 3.7	5.9	188.9 ± 26.6	209.9	0.2
R104E	66.2 ± 6.0	9.2	1115 ± 341	1238.9	0.1