Table 2. Logistic regression analysis of associations between rs1805034 polymorphism and the risk of RA.
| Genotype | Cases (n=574) | Controls (n=804) | OR (95% CI), P | Adjusted OR (95% CI); P | ||
|---|---|---|---|---|---|---|
| n | % | n | % | |||
| RANK rs1805034 | ||||||
| TC vs. TT | 253/266 | 44.3/46.6 | 324/386 | 41.3/49.2 | 1.13 (0.90, 1.42), 0.280 | 1.13 (0.90, 1.42); 0.287 |
| CC vs. TT | 52/266 | 9.1/46.6 | 75/386 | 9.5/49.2 | 1.01 (0.68, 1.48), 0.975 | 0.99 (0.77, 1.27); 0.992 |
| CC+TC vs. TT | 305/266 | 53.4/46.6 | 399/386 | 50.8/49.2 | 1.11 (0.89, 1.38), 0.347 | 1.11 (0.89, 1.37); 0.360 |
| CC vs. TC+TT | 52/519 | 9.1/90.9 | 75/710 | 9.5/90.5 | 0.95 (0.64, 1.38), 0.780 | 0.94 (0.65, 1.37); 0.749 |
| C vs. T | 357/785 | 31.3/68.7 | 474/1096 | 30.2/69.8 | 1.05 (0.89, 1.24), 0.551 | NA |
Adjusted for age and sex. Abbreviation: NA, not available.