Table 3. Expression of recombinant t-PA (or its mutant) in the milk of transgenic animals.

Host animal	Recombinant protein	Signal peptide	Expression (μg/ml)	Ref.
Rabbit	rhPA	BLG	1130–3660	This report
Rabbit	t-PA	Native	0.2–0.85	[41]
Rabbit	t-PA	Native	0.2–0.5	[42]
Rabbit	t-PA	Native	0.05	[43]
Mouse	t-PA	Native	3300	[44]
Mouse	t-PA	Native	3.66	[45]
Mouse	La-tPA	Native	0.18	[46]
Mouse	La-tPA	Native	6	[47]
Goat	La-tPA	Native	3	[48]
Goat	La-tPA	Native	1000–3000	[49]