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. 2019 Jun 28;39(6):BSR20190857. doi: 10.1042/BSR20190857

Figure 6. Effect of higenamine on IL-1β-stimulated activation of NF-κB pathway in NPCs.

Figure 6

(A) The expressions of IκBα, NF-κB p65 and p-p65 were measured using Western blot after stimulation with higenamine (10, 20, 40 μM) in the presence or absence of IL-1β (10 ng/ml) for 1 h. (B,C) Quantification analysis of p-p65/p65 and IκBα/β-actin. (D,E) NF-κB-p65 siRNA-enhanced anti-inflammatory actions of higenamine in IL-1β-stimulated NPCs. *P < 0.05 vs. control NPCs. #P < 0.05 vs. IL-1β-stimulated NPCs. &P < 0.05 vs. IL-1β+ higenamine.